Forcefield_PTM: AMBER Forcefield Parameters for Post-translational Modifications
Forcefield_PTM is a set of self-consistent AMBER forcefield parameters for frequently occurring post-translational modifications (PTMs).
Instructions to Download and Use Forcefield_PTM in AMBER
Download and read the instructions for use.
Download and unzip FF_PTM.
Submit Protein Structure to Be Post-Translationally Modified Multiple Times
Please upload a file containing the position and modifications you would like to add in the following format
An example is the following: Note, this facility is capable of making multiple natural amino acid mutations in tandem with post-translational modifications.
If using the parameters or this web server, please cite the associated publications, which describe the details of our method.
CAF acknowledges support from The National Institutes of Health grant number R01GM052032, and the National Science Foundation. GAK is grateful for support by a National Science Foundation Graduate Research Fellowship under grant number DGE-1148900. This work used the Extreme Science and Engineering Discovery Environment (XSEDE) under allocation TG-MCB110039 to perform simulations on Kraken, which is supported by National Science Foundation grant number OCI-1053575.